The genomic landscape of metastatic histologic special types of invasive breast cancer
نویسندگان
چکیده
منابع مشابه
Sentinel Node Biopsy in Special Histologic Types of Invasive Breast Cancer.
OBJECTIVE To assess the feasibility of sentinel node biopsy (SNB) in ductal and lobular invasive breast cancer, a group of tumors known as special histologic type (SHT) of breast cancer. MATERIALS AND METHODS Between January 1997 and July 2008, 2253 patients from 6 affiliated hospitals underwent SNB who had early breast cancer and clinically negative axilla. The patients' data were collected ...
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Response to drug therapy in individual colorectal cancer (CRC) patients is associated with tumour biology. Here we describe the genomic landscape of tumour samples of a homogeneous well-annotated series of patients with metastatic CRC (mCRC) of two phase III clinical trials, CAIRO and CAIRO2. DNA copy number aberrations of 349 patients are determined. Within three treatment arms, 194 chromosoma...
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BACKGROUND Important differences in the contributions of certain exposures to the risks of ductal versus lobular breast carcinomas have been observed, but few studies have evaluated the relationships between established breast cancer risk factors and other histologic types. METHODS Information on family history of cancer and reproductive, hormonal, anthropometric, and lifestyle characteristic...
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In human breast cancer, estrogen receptor (ER) status of the tumor has prognostic and therapeutic significance. However, facilities to study ER are not widely available to us. We postulated that if there is a correlation between histologic grade and ER status of invasive ductal carcinoma (IDC), it may help predict the ER status of the tumor. Of 8 4 cases of breast carcinoma referred to the ...
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ژورنال
عنوان ژورنال: npj Breast Cancer
سال: 2020
ISSN: 2374-4677
DOI: 10.1038/s41523-020-00195-4